Tuesday, October 23, 2018

The Anti Vax Epidemic - Good Parents Getting Gamed . Episode 1: Autism and Vaccines

I believe all parents want to do what's best for their kids. I really do. And even I, a virologist, had to deal with concerns about vaccines when I found out I was pregnant 12 years ago. For me, that meant doing what I did best: researching and talking to pioneers in the field. To give this topic the attention it deserves, I will be presenting it in several parts; each addressing an important concern that you as parents have when deciding whether or not to vaccinate your children.

Today I'm going to tackle the elephant in the room - Autism.
First let me say I understand your concerns and I won't dismiss them. All good parents want to make sure they are doing what's best. One of the biggest concerns when it comes to vaccines, even now, is that it could give your child autism. And while a lot of people with autism live wonderful and fulfilling lives, no parent wants to give their child autism by making a bad choice, right? Of course not. And there are many people telling you it can happen while others say it can't. So what risk is there, really, of getting autism from a vaccine?

I can tell you confidently, as a scientist and mother who has researched this extensively, that all scientific evidence shows that vaccines do not give children autism. In the early 1990s, this was a valid concern, because it seemed that the incidence of autism was increasing and it seemed to show up around the same time as children were vaccinated. So we absolutely needed to find out if the one caused the other. But we now have 30 years of data showing zero correlation between vaccines and autism. 

First let's look at the perceived increase in the incidence/prevalence of autism. Has there really been an increase? No. The reality is that there has been an increase in the number of kids diagnosed with autism, while the number of kids with autism has not increased.
Let me explain.
What I mean, is that the difference, based on extensive and well-designed studies, is that rather than an increase in the number of people with autism, we are seeing an increase in the number of people identified as having autism. Is there a difference? Yes. It means that previously, there were people on the autism spectrum who were not identified as such. Their numbers were not counted. Now, these people are being identified. This gives the illusion that more people are on the spectrum now, but that's not true, it means we are now finding and identifying those people, and counting them.

This happened for a number of reasons. First, physicians began looking for it. If they looked for it and found it, they diagnosed it. Before the 1990s we weren't looking for it so all but the most severe cases went undetected and undiagnosed. Not only that, but the diagnostic criteria for autism has changed and it became a spectrum disorder - that then means that children who would not have met the previous criteria for autism, but who fall on that spectrum, are now diagnosed as having autism. This alone increases the number of children diagnosed with autism dramatically. So we are looking for it, the criteria to be given the diagnosis has changed, and finally, it's being recognized as something that kids can get help for in school, so parents are more and more willing to accept the diagnosis, even when the child is on the very mild end of the spectrum. Again, this increases the number of kids diagnosed with autism.

When you take all the data on children with autism or on the spectrum, from 1990-2010 we find: "In 2010 there were an estimated 52 million cases of ASDs, equating to a prevalence of 7.6 per 1000 or one in 132 persons. After accounting for methodological variations, there was no clear evidence of a change in prevalence for autistic disorder or other ASDs between 1990 and 2010." From The epidemiology and global burden of autism spectrum disorders. An excellent but more palatable article is The Real Reason Autism Rates are Up in the US.

The bottom line, is that vaccines don't cause autism. Despite what you hear, vaccines do not cause autism. Here is a letter written to President Trump and signed by 9 pages of scientific organizations, asking him to speak out in favor of vaccines, to help curb the anti-vax movement. The reason I've linked it here, is because after the 9 pages of signatures, there are 18 pages of studies - summaries and links - that all show that vaccines do not cause autism. They are powerful evidence of the truth about vaccines.

I understand that there are some loud voices out there working to convince you that autism is a real risk from vaccines. But the truth is that they are using fear to advance their own agendas. Don't let them fool you. Your child's life is at stake. As a scientist, I can say that the people who have done these studies do them so that they can also make the right choices for their own kids. They do everything they need to do, to present reliable and unbiased evidence. This isn't easy and there's no money in it, trust me. In addition, dedicated scientists are, as we speak, working diligently to figure out what actually is causing autism, and they are making progress. The two biggest problems with the anti-vax movement are that in addition to putting your children's lives at risk, they make it really hard for scientists to work on the real problem. Don't give them your support. Our children deserve better.

The child in the picture above has measles. A total of 11 measles outbreaks (3 or more linked cases) have been reported so far in 2018. As of Oct. 6, 2018, 142 individual cases of measles have been confirmed in 25 states and DC. (CDC.gov) Measles kills, yes, but did you know that if someone survives the measles they could have serious long term health problems? One of the most severe is called subacute sclerosing panencephalitis (SSPE) is a very rare, but fatal disease of the central nervous system that results from a measles virus infection. SSPE generally develops 7 to 10 years after a person has measles, even though the person seems to have fully recovered. The risk of developing SSPE is higher for a person who gets measles before they are two years of age.

Other severe complications include pneumonia and encephalitis (swelling of the brain). Patients may need to be hospitalized and could die.  As many as one out of every 20 children with measles gets pneumonia, the most common cause of death from measles in young children. About one child out of every 1,000 with measles will develop encephalitis that can result in convulsions, deafness, or intellectual disability. And finally, for every 1,000 children with measles, one or two will die. There was a reason the measles vaccine was a game changer for parents when it first came out. It saved lives. Vaccines don't cause autism, they cause adults.

Now, it's October, so go get that flu vaccine for you and your children. Last flu season, >80,000 Americans died of the flu, the highest toll in more than ten years according to federal health officials. Of those, 180 were young children and teenagers. Already this year, it was reported just eight days ago, that an unvaccinated child in Florida died from the flu. Don't let your child be the next fatality.

Am I fearmongering too? Maybe, and I'm sorry for that. Well, sorry not sorry. In this case, the danger is all too real. Just ask the mom whose child died eight days ago. She'll tell you just how real.



Sources not linked above:
Gershon AA. Measles virus (rubeola). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Updated Edition. 8th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 162.
Mason WH. Measles. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2016:chap 246.